DEVELOPMENT OF PROCEDURES TO DETERMINE PHOSPHATES IN MEDICATED REMINERALIZING FILMS

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DOI: https://doi.org/None
Issue: 
1
Year: 
2015

E.S. Berezina, PhD; A.L. Golovanenko, PhD; I.V. Alekseeva, PhD; E.V. Tretyakova, PhD Perm State Pharmaceutical Academy; 2, Polevaya St., Perm 614990

To simulate the properties of saliva in remineralizing agents is a new area in enamel remineralization therapy. The composition of medicated films has been designed for active enamel remineralization. Optimal procedures have been proposed for the qualitative and quantitative determination of disubstituted potassium phosphate that is one of the major mineral components of medicated remineralizing films. The latter contributes to the enhanced buffering capacity of saliva and takes an active part in an exchange between saliva and enamel. A photoelectric colorimetric assay is recommended for the qualitative determination of potassium phosphate as a component of the films.
Keywords: 
remineralizing agents
medicated films
disubstituted potassium phosphate
determination
References: 
  1. Golovanenko A.L., Smirnova M.M., Alekseeva I.V., Blinova O.A. Osnovnye podhody k standartizacii plenok lekarstvennyh. Sovremennye problemy nauki i obrazovaniya, 2012; 2 (E`lektronnye resurs / Rezhim dostupa: http://www.science-education.ru/102-5694).
  2. Golovanenko A.L., Berezina E.S., Pavlova G.A., Kozhuhar` V.Yu. Razrabotka sostava i tehnologii gelya dlya remineralizacii e`mali. Materialy mezhdunar. nauch.-metod. konferencii «Sanderovskie chteniya, posvyashh. pamyati vydayushhegosya otechestv. uchenogo v oblasti tehnologii lekarstv Yu.K. Sandera». SPb., 2012; 75–77.
  3. Gosudarstvennaya farmakopeya SSSR XI izd. vyp.1. M.: Medicina, 1987; 335.
  4. Kaliy fosfornokislyy dvuzameshhennyy 3-vodnyy. GOST 2493-75; 7.
  5. Kaliya fosfat (dvuzameshhennyy). FS 42-1297-79; 4.
  6. Homenko L.L., Bidenko N.V. Sovremennye sredstva e`kzogennoy profilaktiki zabolevaniy polosti rta. Kiev: Kniga plyus, 2001; 208