STANDARDIZATION OF SPIRULINA (SPIRULINA PLATENSIS) MASS-BASED SUPPOSITORIES

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DOI: https://doi.org/None
Issue: 
1
Year: 
2015

I.O. Markova; Professor S.V. Pervushkin, PhD; Professor V.A. Kurkin, PhD* Samara State Medical University; 89, Chapaevskaya St., Samara 443099

Dietary spirulina (Spirulina platensis) biomass is one of the promising types of plant raw materials to design drugs having regenerating and antiinflammatory activities. A dosage form, such as suppositories, is commonly used to treat hemorrhoid and gynecological inflammatory diseases. To analyze dietary spirulina biomass-based suppositories, their standardization procedure has been developed. To determine the identity of the suppositories, the authors propose to identify the pigment phycocyanin and to use the spectral characteristics of β-carotene and phycocyanin. Procedures have been devised for the spectrophotometric quantification of β-carotene and phycocyanin. The content of β-carotene and phycocyanin in the suppositories ranges from 0.80 mg to 1.35 mg% and from 0.20 to 0.33%, respectively.
Keywords: 
dietary spirulina (Spirulina platensis)
biomass
β-carotene
phycocyanin
suppositories
standardization
spectrophotometry
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