Farnesol: properties, role, and prospects for use in the regulation of film formation in fungi of the genus Candida

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DOI: https://doi.org/10.29296/25419218-2020-06-02
Issue: 
6
Year: 
2020

N.P. Sachivkina, I.V. Podoprigora, A.I. Marakhova Peoples’ Friendship University of Russia, 6, Miklukho-Maklai St., Moscow 117198, Russian Federation

The paper describes the nature of farnesol, a secondary metabolite of isoprene substances, and its role as a QS-molecule in fungal intra- and interspecific chemocommunication. It discusses chemosignaling systems that regulate fundamental cellular processes, in which farnesol is involved. The authors analyze and systemize data on the use of farnesol in combination with antimycotic drugs against biofilms of yeast-like fungi of the genus Candida spp.
Keywords: 
yeast-like fungi
genus Candida
biofilms
farnesol
QS-molecules
chemocommunication
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