HPLC INVESTIGATION OF FLAVONOIDS IN THE BLACKCURRANT (RIBES NIGRUM L.) BUDS AND LEAVES

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DOI: https://doi.org/None
Issue: 
1
Year: 
2015

T.S. Popova; D.M. Popov, PhD; N.S. Tereshina, PhD* I.M. Sechenov First Moscow State Medical University; 8, Trubetskaya St., Build. 2, Moscow 119991

Blackcurrant (Ribes nigrum L.) buds and leaves having anti-inflammatory and diuretic activities are used in homeopathy and folk medicine. The composition of flavonoids was comparatively examined in these types of the raw materials. HPLC established that the blackcurrent buds and leaves had a varying qualitative composition of flavonoids, which should be borne in mind when deriving medications from these types of the raw materials. The buds of blackcurrant were used to isolate and identify 4 flavonoids, of them there were 2 quercetin derivatives (quercetin-3-O-[malonyl-βD-glucopyranoside] and quercetin-3-O-D-galactopyranoside (hyperoside)) and 2 myricetin ones (myricetin-3-O-[6-O-malonoyl-β-Dglucopyranoside] and myrecitin-3-O-β-D-glucuronide). Its leaves were found to contain 2 quercetin derivatives (quercetin-3-O-[6-O-malonyl-β-Dglucopyranoside] and quercetin-3-O-D-galactopyranoside (hyperoside)) and 2 kaempferol ones (kaempferol-3-O-[6-O-malonoyl-β-Dglucopyranoside] and kaempferol-3-O-D-galactopyranoside). The flavonoids, quercetin derivatives, isolated from blackcurrant buds and leaves are structurally similar.
Keywords: 
blackcurrant (Ribes nigrum L.)
buds
leaves
flavonoids
HPLC
References: 
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