INVESTIGATION OF THE ANTIMICROBIAL ACTIVITY OF A MEDICINAL COMPOSITION CONTAINING EUCALYPTUS AND ECHINACEA EXTRACTS

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DOI: https://doi.org/None
Issue: 
3
Year: 
2016

P.M. Masese (1), T.V. Fateeva (2), Professor P.G. Mizina (1,2), PhD, I.N. Zilfikarov (2), PhD 1 -People’s Friendship University of Russia; 6, Miklukho-Maklai St., Moscow 117198 2 -All-Russian Research Institute of Medicinal and Aromatic Plants; 7, Grin St., Build. 1, Moscow 117216

Medicines that have antimicrobial, anti-inflammatory, decongestant, and local anesthetic effects are used to treat chronic sore throat. Eucalyptus and echinacea extracts-based agents manufactured in various dosage forms (solutions, suppositories, tablets) have proven to be effective. By taking into account a broad spectrum of pharmacological activity of each preparation, it is expedient to design a composition containing eucalyptus and echinacea extracts. The antimicrobial activity of the proposed combined composition versus its individual components, such as a Eucalyptus viminalis Labill. extract and a Echinacea purpura (L) Moench extract, was tested in vitro.
Keywords: 
plant extracts
eucalyptus extract
echinacea extract
pharmaceutical composition
antimicrobial
bacteriostatic
fungistatic activity
test microorganisms
References: 
  1. Ashihmin Ya. Novye perspektivy primeneniya preparatov na osnove e`hinacei. Vrach, 2010; 1: 32–34.
  2. Vichkanova S.A. Novye aspekty primeneniya e`vkalimina. Voprosy biologicheskoy, medicinskoy i farmacevticheskoy himii, 2012; 1: 214–220.
  3. Vichkanova S.A., Kolhir V.K., Sokol`skaya T.A., Voskoboynikova I.V., Bykov V.A. Lekarstvennye sredstva iz rasteniy. (Opyt VILAR). M.: Adris, 2009: 432.
  4. Vichkanova S.A., Krutikova N.M. Klinicheskaya e`ffektivnost` e`vkalimina v kachestve antibakterial`nogo i protivovospalitel`nogo sredstva obshherezorbtivnogo deystviya. Trudy VILAR: «Himiya, tehnologiya, medicina». M., 2000; 347–357.
  5. Gofman V.V. Disbioticheskoe sostoyanie slizistoy obolochki nebnyh mindalin kak lokal`noe proyavlenie sistemnogo mikroe`kologicheskogo disbalansa – osnovnaya prichina vozniknoveniya hronicheskogo tonzillita. Rossiyskaya otorinolaringologiya, 2014; 4 (71): 32–38.
  6. Gofman V.V., Pluzhnikov N.N. Sovremennye predstavleniya ob e`tiopatogeneze hronicheskogo tonzillita. Ross. otorinolaringologiya, 2014; 3 (70): 34–39.
  7. Gofman V.V., Smirnov V.S. Sostoyanie immunnoy sistemy pri ostryh i hronicheskih zabolevaniyah LOR-organov. V kn.: Immunodeficitnye sostoyaniya. (pod red. V.S.Smirnova, I.S.Freydlin). SPb.: Foliant, 2000; 163–187.
  8. Karpishhenko S., Kolesnikov O. Vozmozhnosti lecheniya ostroy boli v gorle. Vrach, 2014;2:19-22.
  9. Krepkova L.V., Bortnikova V.V., Borovkova M.V., Sokol`skaya T.A. Doklinicheskoe toksikologicheskoe issledovanie fitopreparatov iz e`hinacei purpurnoy travy. Voprosy biologicheskoy, medicinskoy i farmacevticheskoy himii, 2012; 1: 178–184.
  10. Krutikova N.M. E`vkalimin – novyy rastitel`nyy preparat antibakterial`nogo deystviya. Dis. …kand. biol. nauk. M., 1997: 100.
  11. Rukovodstvo po provedeniyu doklinicheskih issledovaniy lekarstvennyh sredstv. (pod red. Mironova A.N.). Chast` I . M.: «Grif i K», 2012: 511–526.